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Ingredient

CoQ10 (Ubiquinone/Ubiquinol)

Promising

An endogenous mitochondrial cofactor often supplemented in midlife and older adults.

How it works

Acts as an electron carrier in the mitochondrial electron transport chain and as a lipid-phase antioxidant.

Evidence

The Q-SYMBIO RCT in chronic heart failure used 100 mg three times daily (300 mg/day) and reported improved outcomes. Evidence in healthy adults at lower doses is less direct.

Studies

  • Mortensen et al., JACC Heart Fail, 2014

    100 mg three times daily (300 mg/day) improved outcomes in chronic heart failure.

    PubMed 25282031

Top products

Sorted by effective monthly cost

Now Foods Coq10 100 mg

Now Foods

Per serving
100 mg
Studied midpoint
300 mg · 3/day

Effective cost

$0.65/day·$20/month

Thorne Coq10 100 mg

Thorne

Per serving
100 mg
Studied midpoint
300 mg · 3/day

Effective cost

$1.20/day·$36/month

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